Leon Edwards will make the first defense of his welterweight title Saturday in the main event of UFC 286 in a trilogy showdown against rival Kamaru Usman. The main UFC 286 fight card is set for 5 p.m. ET from the O2 Arena in London.

Usman is a -260 favorite (risk $260 to win $100), while Edwards returns a price of +210 (risk $100 to win $210) in the latest UFC 286 odds for Edwards vs. Usman 3 at Caesars Sportsbook. Before locking in your UFC 286 selections, make sure you hear from SportsLine MMA expert Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who profited more than 62 units in 2022. This includes a documented 24-14 record on his well-respected, two-leg parlays. Every pick was documented on his public Instagram account (@Brasco_Bets). In his SportsLine debut in January, Vithlani went 5-0 on the main card alone to bring $100 bettors a profit of $500! Anyone who has followed him is WAY UP!   

This week at UFC 286: Edwards vs. Usman 3, we can tell you he is backing Gunnar Nelson (-380) to get his hand raised against Bryan Barberena (+300) in a battle of welterweight veterans on the main card.

Vithlani also has strong picks for Edwards vs. Usman 3 and other fights on the UFC 286 card. He's also backing a fighter who is "one of the most dangerous strikers in the UFC" to emerge with a huge victory! You MUST see his UFC 286 picks before making any of your own.

Who wins UFC 286: Edwards vs. Usman 3? And which other fighters to do you need to back? Join SportsLine now to see which fighters you need to be all over Saturday, all from the expert who profited 62 units in 2022!