The UFC welterweight title will be on the line Saturday when champion and top-ranked Kamaru Usman faces top contender Leon Edwards. The main UFC 278 fight card is set for 10 p.m. ET from Vivint Arena in Salt Lake City. Usman is a -400 favorite (risk $400 to win $100), while Edwards is a +310 underdog (risk $100 to win $310) in the latest UFC 278: Usman vs. Edwards 2 odds from Caesars Sportsbook.

Before finalizing any UFC 278: Usman vs. Edwards 2 picks, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley. Over the past three-plus years, $100 bettors who have followed Marley's picks are up more than $13,000! 

The accomplished MMA analyst has provided consistent winners for SportsLine members for the past three-plus years. His accomplishments include hitting five consecutive main-event underdog winners in 2020 following the UFC's brief pause in action because of the pandemic. Anyone who has followed Marley is WAY UP!

This week at UFC 278: Usman vs. Edwards 2, we can tell you Marley is backing Wu Yanan (+100) to get past Lucie Pudilova (-120) in a women's bantamweight matchup.

Marley also has strong picks for Usman vs. Edwards 2 and every other bout on the UFC Fight Night card. He's also backing "a dangerous fighter" to emerge with a dominant victory! You MUST SEE his UFC 278 picks before making any of your own.

Who wins UFC 278: Usman vs. Edwards 2? And which fighter is a MUST-BACK? ... Join SportsLine right now to see which fighters you need to be all over Saturday, all from the expert who's up more than $13,000 on MMA picks!