UConn vs. UCLA odds, prediction: 2026 NCAA Tournament picks from proven model

The UCLA Bruins and UConn Huskies are two of the most accomplished programs in the history of college basketball and they'll go head-to-head on Sunday in the second round of the 2026 NCAA Tournament. UConn is 30-5 on the season and beat Furman 82-71 on Friday while UCLA is 24-11 and edged out UCF in the first round 75-71.

Tipoff from the Wells Fargo Center in Philadelphia is at 8:45 p.m. ET. The Huskies are 4.5-point favorites in the latest UConn vs. UCLA odds, while the over/under is 137.5. 

Before making any UCLA vs. UConn picks, you NEED to see the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered the 2026 NCAA Tournament on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on a 28-22 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated UConn vs. UCLA 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits nearly 60% of the time!

So who wins UCLA vs. UConn, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!