UConn vs. St. John's odds, prediction: 2026 Big East Tournament Championship picks from proven model

The 2026 Big East Tournament concludes on Saturday with a championship matchup between top-seeded St. John's and No. 2 seed UConn. Both teams have won every game in this tournament by double digits, and now they meet for a rubber match after splitting their regular season matchups. 

Tipoff from Madison Square Garden in New York is set for 6:30 p.m. ET. The Huskies are 2.5-point favorites in the latest UConn vs. St. John's odds, while the over/under is 140.5. Before making any St. John's vs. UConn picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered conference tournament week on a sizzling 14-2 run on top-ranked over/under picks dating back to last year, and is on an 28-21 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated this matchup 10,000 times and the results are in. The model is going Over, and it also says one side of the spread hits well over 60% of the time!

So who wins UConn vs. St. John's, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!