UConn vs. Michigan odds, prediction: 2026 NCAA Tournament picks from proven model

The Michigan Wolverines will look to end the Big Ten Conference's 26-year men's basketball title drought when they battle the Connecticut Huskies in the NCAA Tournament national championship game on Monday night. Michigan State was the last Big Ten team to earn the crown, defeating Florida in 2000. The Huskies (34-5), who have won six national titles, all since 1999, advanced with a 71-62 win over Illinois in Saturday's national semifinal. The Wolverines (36-3), who are looking for their second national title and first since 1989, defeated Arizona 91-73 on Saturday.

Tip-off from Lucas Oil Stadium in Indianapolis is set for 8:49 p.m. ET. The all-time series is tied 2-2, with UConn earning a 74-60 win in their last meeting on Nov. 25, 2015. Michigan is a 6.5-point favorite in the latest UConn vs. Michigan odds, while the over/under for total points scored is 144.5. 

Before making any UConn vs. Michigan picks, you NEED to see the basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered the 2026 Final Four on a sizzling 11-1 run on its top-rated over/under college basketball picks dating back to last season, and is on a 28-22 run on top-rated CBB side picks. 

The model has simulated UConn vs. Michigan 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits well over 60% of the time!

So who wins Michigan vs. UConn, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!