UConn vs. Michigan odds, prediction: 2026 NCAA Tournament picks from proven expert on 38-25 run

The second-seeded Connecticut Huskies look to win their seventh national championship title, all since 1999, when they battle the top-seeded Michigan Wolverines in the 2026 NCAA Tournament national championship game on Monday night. UConn is coming off a 71-62 win over Illinois, while Michigan downed Arizona 91-73 in Saturday's semifinals. The Huskies (34-5), who finished second in the Big East at 17-3, are looking to win their third national title over the past four years. The Wolverines (36-3), who won the Big Ten regular season title at 19-1, are seeking to win their first national championship since 1989.

Tipoff from Lucas Oil Stadium in Indianapolis is set for 8:49 p.m. ET. The all-time series is tied 2-2, with UConn earning a 74-60 win in their last meeting on Nov. 25, 2015. Michigan is a 6.5-point favorite in the latest UConn vs. Michigan odds, while the over/under for total points scored is 144.5. 

Before making any UConn vs. Michigan picks, check out what SportsLine college basketball expert Thomas Casale has to say.

A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting - and winning - for more than 30 years. He sets his own lines for each game, then looks at the metrics to see where he can find an edge in the number. Over the past three college basketball seasons, Casale is 402-247 (62 percent) - all publicly documented. He joined SportsLine in early 2024 and has gone 89-53 in college basketball, returning $2,968 to $100 players, and he enters this matchup on a 38-25 roll on CBB spread picks!

Now Casale has broken down UConn vs. Michigan from every angle and locked in his picks. He's leaning Over on the total, and he's also found a critical X-factor that has him jumping on one side the spread! 

So who covers in Michigan vs. UConn, and what critical X-factor do you need to know about? Join SportsLine right now to see which side of the spread you need to jump on, all from the expert on a sizzling 38-25 run on CBB spread picks!