UConn vs. Marquette odds, prediction: 2026 Big East men's college basketball picks from proven model

The fourth-ranked UConn Huskies meet the Marquette Golden Eagles in a Big East clash on Saturday. UConn is coming in well-rested, having not played since last Saturday's 71-67 victory at home over Seton Hall. Marquette is also coming off a 78-56 win at Providence. The Huskies (27-3, 17-2 Big East) will stay in the mix for a possible No. 1 NCAA Tournament seed and at least a share of the Big East title with a win over Marquette can secure at least a share of the Big East title and stay in the mix for a possible No. 1 NCAA Tournament seed by defeating Marquette. The Golden Eagles (11-19, 6-13 Big East), who are 10th out of 11 teams in the conference, are 9-7 on their home court.

Tipoff from Fiserv Forum in Milwaukee, Wisc., is set for 12:30 p.m. ET. The two teams have played once already this season, resulting in a sizable 73-57 win at home for the UConn Huskies. UConn is a 9.5-point favorite in the latest UConn vs. Marquette odds from DraftKings Sportsbook, while the over/under for total points scored is 143.5. 

Before making any Marquette vs. UConn picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered Week 18 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 23-17 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated UConn vs. Marquette 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits in well over 50% of simulations!

So who wins UConn vs. Marquette, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!