UCLA vs. No. 2 Indiana odds, line: 2025 college football picks for Week 9 predictions from proven model

The UCLA Bruins look to stay hot when they take on the second-ranked Indiana Hoosiers in a key Big Ten matchup on Saturday. UCLA is coming off a 20-17 win over Maryland in Week 8, while Indiana downed Michigan State 38-13. The Bruins (3-4, 3-1 Big Ten), who have won three in a row and are tied for third in the conference, are 1-2 on the road this season. The Hoosiers (7-0, 4-0 Big Ten), who are tied with top-ranked Ohio State for first in the conference, are 5-0 on their home field.

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Kickoff from Memorial Stadium in Bloomington, Ind., is at noon ET. Indiana leads the all-time series 1-0, winning last year's meeting 42-13 in Los Angeles. The Hoosiers are 26.5-point favorites in the latest UCLA vs. Indiana odds, while the over/under for total points scored is 53.5 via SportsLine consensus. 

Before making any UCLA vs. Indiana picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 42-30 combined on money-line and over/under picks since the beginning of 2024. Anyone following at sportsbooks and on betting apps could have seen STRONG returns!

The model has simulated UCLA vs. Indiana 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in well over 60% of simulations!

So who wins UCLA vs. Indiana, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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