Twins vs. White Sox odds, lines: Proven model reveals MLB picks for Monday's Game 1 matchup

The Chicago White Sox look to continue their dominance in the season series when they host the Minnesota Twins in Game 1 of the doubleheader between the American League Central rivals on Monday. 

First pitch in this seven-inning matchup from Guaranteed Rate Field is set for 5:10 p.m. ET. The White Sox are listed as -219 favorites (risk $219 to win $100) on the money line in the latest Twins vs. White Sox odds from William Hill Sportsbook, while the over-under for total runs scored is seven (see the latest lines for every game on our MLB odds page).

Before making any Twins vs. White Sox Game 1 picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. In the first half of the 2021 season, it went 120-96 on top-rated MLB money-line picks, returning almost $400. Anyone following it has seen HUGE returns!

Now, it has set its sights on Game 1 of Twins vs. White Sox. We can tell you it's leaning Over, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Twins vs. White Sox Game 1? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the White Sox vs. Twins money line you should be all over on Monday, all from the model that is up nearly $400 on MLB picks in 2021!