The Cincinnati Reds go for a three-game sweep of the Minnesota Twins when they meet in an interleague matchup on Thursday afternoon. The Twins (36-37), who have lost six in a row, are 16-25 on the road in 2025. The Reds (39-35), who have won four in a row, are 20-16 on their home field this season.

First pitch from Great American Ball Park in Cincinnati is set for 12:40 p.m. ET. The Reds have won six of the past nine meetings with the Twins. Cincinnati is a -114 favorite on the money line (risk $114 to win $100) in the latest Twins vs. Reds odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over-under, is 9 in the latest MLB odds. 

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The model has simulated Twins vs. Reds 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

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