Tulane vs. UTSA odds, line: 2025 college football picks for Week 10 predictions from proven model

The Tulane Green Wave will look to stay perfect in conference play when they take on the UTSA Roadrunners in American Conference action on Thursday. Tulane is coming off a 24-17 win over Army on Oct. 18, while UTSA dropped a 55-17 decision at North Texas that same day. The Green Wave (6-1, 3-0 American), who have won three in a row, are 2-1 on the road this season. The Roadrunners (3-4, 1-2 American), who have lost two of three, are 2-1 on their home field.

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Kickoff from the Alamodome in San Antonio is at 7:30 p.m. ET. The all-time series is tied 1-1, with each school winning at home. The Green Wave are 5.5-point favorites in the latest Tulane vs. UTSA odds, while the over/under for total points scored is 54.5 via SportsLine consensus. Tulane is at -222 on the money line (risk $222 to win $100), while UTSA is at +183 (risk $100 to win $183).

Before making any Tulane vs. UTSA picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks, and it enters Week 10 on a profitable 47-33 combined run on money-line and over/under picks since the beginning of 2024. Anyone following could have seen impressive returns.

The model has simulated Tulane vs. UTSA 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in almost 60% of simulations.

So who wins Tulane vs. UTSA, and which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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