The Tulane Green Wave will take on the Massachusetts Minutemen at 7 p.m. ET on Saturday at Benson Field at Yulman Stadium. UMass ended last year with a 1-11 record, tied for the worst in FBS, while the Green Wave weren't far ahead at 2-10. 

The Green Wave are favored by 28 points in the latest Tulane vs. Massachusetts odds from Caesars Sportsbook, and the over-under is set at 59. Before you make any UMass vs. Tulane picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football side picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Tulane vs. UMass 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in 70 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Tulane vs. Massachusetts? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!