The Minnesota Timberwolves take on the Los Angeles Lakers in an early-season key NBA Western Conference matchup on Friday night. Minnesota is coming off a 118-114 win at Portland on Wednesday, while Los Angeles dropped a 119-109 decision to Golden State on Tuesday. The Timberwolves (1-0), who finished sixth in the conference a year ago at 49-33, are 25-17 on the road since the start of last season. The Lakers (0-1), who were the third seed in the West at 50-32 in 2024-25, are 31-11 at home since last October. 

Tipoff from Crypto.com Arena in Los Angeles is set for 10 p.m. ET. The Lakers lead the all-time series 87-46, but the teams split four games last season. Minnesota is a 2.5-point favorite in the latest Timberwolves vs. Lakers odds from SportsLine consensus, while the over/under for total points scored is 225.5. 

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