Thunder vs. Knicks odds, line: Proven model reveals picks for NBA matchup on Wednesday, March 4

The Oklahoma City Thunder battle the New York Knicks in a key NBA matchup on Wednesday night. Oklahoma City is coming off an NBA championship last season. New York, meanwhile, is looking to make the postseason for the fourth consecutive season. The Thunder, who are the top seed in the Western Conference, have a plus-11.3 points differential this season. The Knicks, who are third in the East, are 23-8 on their home floor in 2025-26. OKC is expected to be without Jalen Williams (hamstring), while Miles McBride (ankle) is out for New York.

Tip-off from Madison Square Garden in New York is set for 7 p.m. ET. The Thunder lead the all-time series 75-68, including wins in each of the last four meetings The Thunder are a 3.5-point favorite in the latest Thunder vs. Knicks odds from. DraftKings Sportsbook, while the over/under for total points scored is 222. 

Before making any Thunder vs. Knicks picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered Week 20 on a sizzling 41-18 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Thunder vs. Knicks 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits well over 50% of the time?

Who wins Thunder vs. Knicks, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 41-18 roll on top-rated NBA picks!