Texas A&M vs. South Carolina odds, line: 2025 college football picks for Week 12 predictions from proven model

The No. 3 Texas A&M Aggies (9-0, 6-0 SEC) will look to remain unbeaten when they host the South Carolina Gamecocks (3-6, 1-6 SEC) on Saturday. A&M is one of three undefeated FBS teams left standing and is coming off a 38-17 victory over then-No. 22 Missouri on Saturday. South Carolina has lost four straight and fell to Ole Miss, 30-14, on Nov. 1 before having a bye last week. The Gamecocks prevailed versus the Aggies in their 2024 meeting, winning 44-20.

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Kickoff is at noon ET from Kyle Field in College Station, Texas. The Aggies are 17.5-point favorites in the latest Texas A&M vs. South Carolina odds, while the over/under for total points scored is 49.5 via SportsLine consensus. 

Before making any South Carolina vs. Texas A&M picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anyone following could have seen impressive returns.

The model has simulated Texas A&M vs. South Carolina 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits nearly 60% of the time!

So who wins South Carolina vs. Texas A&M, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the Texas A&M vs. South Carolina spread you need to jump on, all from the computer model that has crushed its college football picks!

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