Texas A&M vs. Saint Mary's odds, prediction: 2026 NCAA Tournament picks from proven model

The 2026 NCAA Tournament features 16 games on Thursday, and one of the more intriguing matchups is No. 10 seed Texas A&M vs. No. 7 Saint Mary's in the South Region. The Aggies went 21-11 and tied for fourth in the SEC at 11-7.  Saint Mary's, meanwhile, went 27-5 overall and split the WCC regular-season title with Gonzaga at 16-2. The winner advances to take on the winner of Houston vs. Idaho. 

Tipoff from the Paycom Arena in Oklahoma City is at 7:35 p.m. ET. The Gaels are 2.5-point favorites in the latest Saint Mary's vs. Texas A&M odds, with the over/under at 147.5. 

Before making any Texas A&M vs. Saint Mary's picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered the 2026 NCAA Tournament on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on a 28-22 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Texas A&M vs. Saint Mary's 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits nearly 60% of the time!

So who wins Saint Mary's vs. Texas A&M, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!