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Trevor Lawrence and the Jacksonville Jaguars, fresh off a come-from-behind win over the Philadelphia Eagles in London, stay in England to take on CJ Stroud and the Houston Texans in an NFL Week 6 matchup. The Jaguars (4-1) sit atop the AFC South despite ranking in the middle of the pack on both sides of the ball. The Texans (1-4) finally earned their first win last Sunday, a blowout of the Titans. Despite the record, Houston actually ranks higher in total offense and total defense than Jacksonville. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 9:30 a.m. ET from Wembley Stadium in London. The latest Texans vs. Jaguars odds have Jacksonville as a 2.5-point favorite. The over/under for total points scored is 42.5.
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Now, the model has locked in another confident pick for Texans vs. Jaguars in the NFL Week 6 2026 matchup.
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