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Texans vs. Chargers prediction, odds: Proven model releases 2025 NFL Week 17 picks for Saturday matchup

The SportsLine projection model, which is on a 53-37 run on top-rated picks dating back to 2024, reveals its Chargers vs. Texans picks for Saturday

ByUpdated: Dec 24, 2025 3:18PM UTC . 2 min read

A potential AFC playoff preview on Saturday has the Houston Texans visiting the Los Angeles Chargers. Houston (10-5) clinches a playoff berth with a victory, and the Texans have won seven straight games. Los Angeles (11-4) has already locked up a postseason spot and is riding a four-game win streak. Houston defeated L.A., 32-12, in a playoff game in Jan. 2025.

Kickoff is at 4:30 p.m. ET from SoFi Stadium in Inglewood, Calif. The latest Texans vs. Chargers odds have Los Angeles favored by 2.5 points, while the over/under for total points is 39.5

Before making any Chargers vs. Texans picks, or 2025 NFL Week 17 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Texans vs. Chargers.

We can tell you it's leaning Over the point total, but also says that one side of the spread hits over 50% of the time! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Chargers vs. Texans in NFL Week 17, and which side of the spread is the better value? ... Join SportsLine RIGHT NOW to see which side of the Texans vs. Chargers line to back, all from the model that has gone 53-37 on top-rated picks since 2024!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1 JOIN NOW. 

GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

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Ross Kelly
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