The Tennessee Volunteers take on the No. 17 Pittsburgh Panthers in a high-profile showdown at 3:30 p.m. ET on Saturday. Tennessee is favored by 6 points at Caesars Sportsbook, while the over/under is set at 62.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Tennessee vs. Pittsburgh picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

The model knows Tennessee's offense is electric. Returning standout Hendon Hooker leads a prolific attack that scored 59 points and racked up 569 total yards in the season opener. Tennessee has scored 45 points or more in four straight games, and the Vols averaged 39.3 points per game in 2021, a top-10 mark in FBS. The model also knows Pittsburgh is coming off its best season since 1981, as the Panthers won 11 games in 2021. Pittsburgh also opened the season with an impressive win over West Virginia, and the Panthers have the most sacks on defense of any FBS program since the start of the 2020 season.

Now, it has set its sights on Tennessee vs. Pittsburgh. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in more than 50% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Tennessee vs. Pittsburgh? And which side of the spread hits in more than 50% of simulations? ... Join SportsLine right now to find out which side of the Tennessee vs. Pittsburgh spread you should be all over Saturday, all from the model on a roll on college football picks!