TCU vs. Oklahoma odds, line, spread: Proven model reveals college football picks, predictions for Week 5, 2022

A Big 12 battle is on tap between the TCU Horned Frogs and the No. 18 Oklahoma Sooners at noon ET on Saturday at Amon G. Carter Stadium. Oklahoma won its first three games of the season before losing to Kansas State as a 13.5-point favorite last week. The Sooners are 6-point favorites in the latest TCU vs. Oklahoma odds from Caesars Sportsbook, while the over/under is set at 69. 

Before making any Oklahoma vs. TCU picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated TCU vs. Oklahoma 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins TCU vs. Oklahoma? And which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.