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Syracuse vs. No. 6 Duke odds, line: Advanced model reveals college basketball picks, predictions for Jan. 22, 2022

SportsLine's projection model generated selections for Saturday's matchup between Duke and Syracuse
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An ACC battle will take place when Syracuse (9-9) and No. 6 Duke (14-3) match up on Saturday afternoon. Duke had their two-game win streak halted. In their last game, Florida State upset the Blue Devils 79-78 in an overtime bout. Syracuse picked up a conference win in their previous outing. The Orange beat Clemson 91-78. Duke is favored by 11.5 points and the over-under for total points is set at 154 at Caesars Sportsbook.

Before making any Syracuse vs. Duke picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.  

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Duke freshman forward Paolo Banchero is leading the way for the Blue Devils. He is leading the team in scoring (18.1), rebounds (7.6) while shooting 51% from the field. Banchero has scored at least 20 points in four straight games. In the overtime loss to Florida State, the Washington native had 20 points, 12 rebounds, and seven assists. 

The model also knows Syracuse senior guard Buddy Boeheim is averaging a team-high 19.2 points with 3.7 rebounds and 3.7 assists. Boeheim has scored 20-plus in eight games thus far. The New York native had a good performance in the win over Clemson. Boeheim dropped 25 points, five rebounds, and two steals in the contest. He also knocked down four 3-pointers. 

Now, it has set its sights on Syracuse vs. Duke. We can tell you the model is leaning under the total and it also says one side of the spread hits in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Syracuse vs. Duke? And which side of the spread has hits in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of Syracuse vs. Duke spread you should be all over Saturday, all from the model on a roll on college basketball picks!

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SportsLine Staff