The Pittsburgh Steelers (5-3-1) and Los Angeles Chargers (5-4) will face off in an AFC battle on Sunday Night Football. The Steelers were without starting quarterback Ben Roethlisberger against the Detroit Lions in Week 10. Roethlisberger was placed on the COVID-19 reserve list, and Pittsburgh's game against Detroit ended in a 16-16 tie. The Chargers couldn't win their second straight game and were defeated 27-20 by the Minnesota Vikings. 

Kickoff from SoFi Stadium is set for 8:20 p.m. ET. Los Angeles is favored by six points in the latest Steelers vs. Chargers odds from Caesars Sportsbook, while the Over-Under is 47.5. Before making you make any Steelers vs. Chargers picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up almost $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 11 of the 2021 season on an incredible 128-89 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model knows Chargers quarterback Justin Herbert has completed 65 percent of his passes for 2,545 yards with 19 passing touchdowns. He is also fifth in the NFL with a QBR of 63.5. Herbert has thrown for more than 300 yards in four games this season. 

The model also knows Steelers rookie running back Najee Harris is a workhorse. Harris is second in the NFL in carries (176) and sixth in rushing yards (646). The 2021 first-round pick has scored four rushing touchdowns while catching another two through the air.

Now, the model has set its sights on Steelers vs. Chargers on Sunday Night Football. We can tell you it's leaning under the total, and it also says one side of the spread cashes in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any Steelers vs. Chargers picks of your own.

So who wins Steelers vs. Chargers on Sunday Night Football? And which side of the spread hits well over 50 percent of the time? ... Join SportsLine right now to see which side of the Steelers vs. Chargers spread to back, all from the dialed-in NFL model that's up almost $7,500 on top-rated picks!