St. John's vs. Kansas odds, prediction: 2026 NCAA Tournament picks from proven model

The fifth-seeded St. John's Red Storm meet the fourth-seeded Kansas Jayhawks in the second round of the NCAA Tournament East Region on Sunday. St. John's defeated Northern Iowa 79-53 in the first round on Friday, while Kansas outlasted California Baptist 68-60. The Red Storm (29-6), who won the Big East Conference at 18-2 and earned the conference tournament title, have won seven games in a row. The Jayhawks (24-10), who tied for third in the Big 12 at 12-6, have won three of their last four.

Tip-off from Viejas Arena in San Diego is set for 5:15 p.m. ET. Kansas leads the all-time series 9-5, including a 95-75 win in 2021. St. John's is a 3.5-point favorite in the latest St. John's-Kansas odds, while the over/under for total points scored is 144.5. Before making any St. John's vs. Kansas picks, you NEED to see the basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered the 2026 NCAA Tournament on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on a 28-22 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated St. John's vs. Kansas 10,000 times and the results are in. The model is going Under on the total, and it also says one side of the spread hits in nearly 60% of the simulations!

So who wins St. John's vs. Kansas, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!