SMU vs. Cincinnati odds, line, spread: Proven model reveals college football picks, predictions for Week 8, 2022

An American Athletic battle is on tap between the SMU Mustangs and the Cincinnati Bearcats at noon ET on Saturday at Gerald J. Ford Stadium. No. 21 Cincinnati has bounced back from a season-opening loss to Arkansas with a five-game winning streak and is coming off a bye. The Bearcats are favored by 3.5 points in the latest SMU vs. Cincinnati odds from Caesars Sportsbook, while the over/under is set at 58.5. 

Before you make any Cincinnati vs. SMU picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated SMU vs. Cincinnati 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins SMU vs. Cincinnati? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.