No. 1 seed Jannik Sinner will try to extend his 19-match winning streak in grand slams when he faces three-time French Open champion Novak Djokovic in the men's French Open semifinals on Friday afternoon. Sinner has won 11 of his last 12 matches against top-10 opponents, with all 11 wins coming in straight sets. Djokovic knocked out No. 3 seed Alexander Zverev in the quarterfinals to advance to the 51st grand slam semifinal of his storied career.  

The Sinner vs. Djokovic match will begin at 1 p.m. ET on Friday on Court Philippe-Chatrier in Paris. Sinner is the -480 favorite (risk $480 to win $100) in the latest Djokovic vs. Sinner odds, while Djokovic is the +360 underdog (risk $100 to win $360). The over/under for total games is 36.5, with Sinner favored by 5.5 games. 

Before you make any French Open picks or predictions, you must see the French Open 2025 picks from tennis handicapper Jose Onorato.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players.

Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bets. He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach has helped Onorato go 168-106-9 (+107.12 units) since 2022. He correctly called Iga Swiatek (-160) in the 2024 French Open and Aryna Sabalenka (+225) in the 2025 Australian Open.

Now, Onorato has taken a close look at this Djokovic vs. Sinner French Open men's singles semifinal from all sides and locked in his best bets! You ABSOLUTELY need to see what they are before locking in any 2025 French Open picks of your own!

So where does all the value lie in the Sinner vs. Djokovic French Open semifinal, and what over/under bet is a must-back? ... Join SportsLine right now to see Jose Onorato's predictions and analysis for the 2025 French Open men's singles semifinal, all from the tennis expert who is 168-106-9 since 2022!