Seahawks vs. Chiefs prediction, odds, line, spread: Proven model reveals NFL picks, best bets for Week 16, 2022

Patrick Mahomes and the Kansas City Chiefs are looking to keep pace in the race for the top seed in the AFC Playoffs when they host Geno Smith and the Seattle Seahawks at 1 p.m. ET on Saturday at GEHA Field at Arrowhead Stadium. The Chiefs are 11-3 overall and 5-1 at home, while Seattle is 7-7 overall and 4-3 on the road. Kansas City is ranked first in the AFC West; the Seahawks are ranked second in the NFC West. The Chiefs are 4-9-1 against the spread, while Seattle is 6-8 ATS in 2022.

Kansas City is favored by 10 points in the latest Chiefs vs. Seahawks odds from Caesars Sportsbook, and the over/under is set at 50.5. Before you make any Seahawks vs. Chiefs picks or predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season. The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, it has simulated Chiefs vs. Seahawks 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread has ALL the value. You absolutely need to see it before locking in your own picks.

So who wins Chiefs vs. Seahawks? And which side of the spread has ALL the value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.