An NFC South battle is on tap between the New Orleans Saints and the Carolina Panthers at 1 p.m. ET on Sunday at Caesars Superdome. The Saints are riding a three-game winning streak following an upset win at Philadelphia last week, but they have been eliminated from playoff contention. New Orleans is favored by 3.5 points in the latest Saints vs. Panthers odds from Caesars Sportsbook, while the over/under is set at 41.5.

Before you make any Panthers vs. Saints picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season. 

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has simulated Saints vs. Panthers 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Saints vs. Panthers? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.