Saints vs. Colts odds, line, spread: Proven model reveals NFL picks, predictions for Week 8, 2023

The New Orleans Saints travel north in Week 8 to take on the Indianapolis Colts in a battle of 3-4 teams looking to get back to .500 on the season. New Orleans fell last Thursday night to Jacksonville, 31-24, while Indianapolis came up short in a wild game, 39-38 vs. Cleveland. The Saints have won the last four meetings, including Super Bowl XLIV in 2010, a 31-17 victory in a game quarterbacked by legends Drew Brees and Peyton Manning. The most recent matchup was in 2019, a 34-7 New Orleans victory at the Superdome.

Kickoff from Lucas Oil Stadium is set for 1 p.m. ET. New Orleans is a 2-point favorite in the Colts vs. Saints odds via SportsLine consensus, while the over/under is 43.5. Before making any New Orleans vs. Indianapolis picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 8 of the 2023 NFL season on an incredible 173-122 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 27-14 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY up!

Now, it has simulated Colts vs. Saints 10,000 times and the results are in. We can tell you that the model is leaning Over the total, and it also says one side of the spread hits well over 50% of the time! You ABSOLUTELY need to see it before locking in your own picks. 

So who wins Saints vs. Colts? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is on a 173-122 roll on its NFL picks!