Saint Louis vs. St. Bonaventure odds, prediction: 2026 Atlantic 10 Conference men's college basketball picks from proven model

The 24th-ranked Saint Louis Billikens will look to extend their winning streak to 13 games when they take on the St. Bonaventure Bonnies in a key Atlantic 10 Conference matchup on Friday. Saint Louis is coming off an 81-77 win over Duquesne on Tuesday, while St. Bonaventure downed Loyola Chicago 84-70 that same night. The Billikens (18-1, 6-0 Atlantic 10), who have won 15 games by double digits, are 4-0 on the road this season. The Bonnies (12-7, 1-5 Atlantic 10), who are 0-1 against ranked opponents, are 8-2 on their home floor.

Tipoff from Reilly Center in St. Bonaventure, N.Y., is set for 5:30 p.m. ET. Saint Louis leads the all-time series 17-16, including wins in each of the last four meetings. Saint Louis is a 8.5-point favorite in the latest Saint Louis vs. St. Bonaventure odds from DraftKings Sportsbook, while the over/under for total points scored is 157.5. 

Before making any Saint Louis vs. St. Bonaventure picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 12 on a sizzling 10-1 run on top-ranked over/under picks. Anyone following could have seen HUGE returns!

The model has simulated Saint Louis vs. St. Bonaventure 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in over 50% of simulations!

So who wins Saint Louis vs. St. Bonaventure, and which side hits over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!