The Saint Joseph's Hawks begin their quest for a fifth Atlantic 10 Conference tournament title when they take on the La Salle Explorers in a first-round game on Wednesday. Saint Joseph's (11-18, 5-13), which last won the conference tournament championship in 2016, halted its seven-game losing streak with a 70-60 victory against Rhode Island in its regular-season finale. La Salle (10-18, 5-13) won its final three contests after having dropped five in a row and 10 of 11.

Tipoff from Capital One Arena in Washington, DC is set for 1 p.m. ET. The Hawks are 2.5-point favorites in the latest Saint Joseph's vs. La Salle odds from Caesars Sportsbook, while the over-under for total points scored is 133. (See up-to-date odds for every game this week on our college basketball odds page.)

Before making any La Salle vs. Saint Joseph's picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Saint Joseph's is seeking quick revenge as it dropped a 49-48 decision at La Salle last Wednesday, marking the second time it lost to the Explorers this season. The Hawks bounced back three days later to defeat the Rams as Erik Reynolds II scored a season-high 27 points on 10-of-14 shooting, including 5-of-8 from 3-point range. The freshman guard, who is third on the team with an average of 12.3 points, has gone 14-for-27 from beyond the arc over his last four games 

The model also knows La Salle wrapped up its regular season with an 85-76 triumph at Duquesne on Saturday. Only two players scored in double figures, but junior guard Jack Clark went 13-for-19 from the floor - including 4-for-6 from long distance - en route to a career-high 30 points and Josh Nickelberry added 23 off the bench. It was the junior guard's best offensive performance since he recorded 24 points on Dec. 7 against Fairleigh Dickinson.

Now, the model has set its sights on Saint Joseph's vs. La Salle. We can tell you it is leaning Over the total, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Saint Joseph's vs. La Salle? And which side of the spread has all the value? ... Join SportsLine right now to find out which side of the La Salle vs. Saint Joseph's spread you should be all over Wednesday, all from the model on a roll on college basketball picks!