Rutgers vs. USC odds: 2025 college basketball picks, February 23 best bets by proven model

We've got another exciting Big Ten matchup on the schedule as the Rutgers Scarlet Knights and USC Trojans are set to tip at 6 p.m. ET on Sunday at Jersey Mike's Arena. Rutgers is 13-14 overall and 9-5 at home, while USC is 14-12 overall and 3-4 on the road. Rutgers is favored by 3.5 points in the latest Rutgers vs. USC odds, and the over/under is 152.5 points.

Before entering any USC vs. Rutgers picks, you'll want to see the college basketball predictions from the advanced computer model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 16 of the 2024-25 season on a 213-158 betting roll (+1675) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Rutgers vs. USC 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that hits in well over 50% of simulations. 

So who wins Rutgers vs. USC? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.