Rutgers vs. No. 1 Ohio State odds, line: 2025 college football picks for Week 13 predictions from proven model

The top-ranked and defending national champion Ohio State Buckeyes look to stay perfect when they take on the Rutgers Scarlet Knights on Saturday. Rutgers is coming off a 35-20 win over Maryland on Nov. 8, while Ohio State cruised to a 48-10 win over UCLA last Saturday. The Scarlet Knights (5-5, 2-5 Big Ten), who have lost five of seven, are 1-3 on the road this season. The Buckeyes (10-0, 7-0 Big Ten), who have won 14 in a row, are 6-0 on their home field. Ohio State star receivers Jeremiah Smith and Carnell Tate are both out for this matchups with injuries. 

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Kickoff from Ohio Stadium in Columbus, Ohio, is at noon ET. Ohio State leads the all-time series 10-0. The Buckeyes are 30.5-point favorites in the latest Rutgers vs. Ohio State odds, while the over/under for total points scored is 53.5 via SportsLine consensus. 

Before making any Rutgers vs. Ohio State picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.

The model has simulated Rutgers vs. Ohio State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits nearly 60% of simulations.

So who wins Rutgers vs. Ohio State, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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