Rockets vs. Pistons odds, line: Proven model reveals picks for NBA matchup on Friday, January 23

The Houston Rockets look to get back on track when they take on the Central Division-leading Detroit Pistons in key NBA action on Friday night. Houston is coming off a 128-122 loss to the Philadelphia 76ers on Thursday, while Detroit posted a 112-104 win over the New Orleans Pelicans on Wednesday. The Rockets (26-16), who are second in the Southwest Division, are 11-13 on the road this season. The Pistons (32-10), who are 10-4 against Western Conference foes, are 17-4 on their home court.

Tip-off from Little Caesars Arena in Detroit is set for 7 p.m. ET. The Pistons lead the all-time series 77-75, and have won two straight in the series. Detroit is a 4.5-point favorite in the latest Rockets vs. Pistons odds from DraftKings Sportsbook, while the over/under for total points scored is 217.5. Before making any Rockets vs. Pistons picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 14 of the 2025-26 NBA season on a sizzling 35-15 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Rockets vs. Pistons 10,000 times and the results are in. We can tell you that the model is going Over on the point total, and it also says one side of the spread hits in well over 50% of simulations!

Who wins Rockets vs. Pistons, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 35-15 roll on top-rated NBA picks!