Rams vs. Vikings prediction, odds, spread, lines: Proven NFL simulation model reveals picks for Week 16 game

The Los Angeles Rams (10-4) have rattled off three straight wins and are a threat to take control of the NFC West from the Arizona Cardinals (10-4) ahead of Week 16. They'll travel to U.S. Bank Stadium n Sunday to take on the Minnesota Vikings. Kickoff is set for 1 p.m. ET, and the Rams are three-point favorites in the latest Rams vs. Vikings odds from Caesars Sportsbook. The over-under for total points scored is 49.

Before making any Rams vs. Vikings picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 16 of the 2021 season on an incredible 133-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows Matthew Stafford has transformed the Rams' passing attack. Los Angeles ranks fourth in passing yards (3,944) and second in passing touchdowns (35). Cooper Kupp leads the NFL in receiving yards (1,625) and receiving touchdowns (14), so the Vikings' secondary is in for a test.

The model also knows Minnesota excels at pressuring quarterbacks. The Vikings rank first in team sacks (44) and sack yardage (319). Stafford could be pressed for time against one of the league's best pass rushes.

Now, the model has set its sights on Rams vs. Vikings. We can tell you it is leaning Onder, and it also says one side of the spread cashes in more than 50 percent of simulations! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Rams vs. Vikings on Sunday? And which side of the spread hits more than 50 percent of the time? ... Join SportsLine right now to find out which side of the Rams vs. Vikings spread you need to jump on, all from the model on a 133-96 roll on NFL picks!