Rams vs. Cardinals prediction, odds, line, spread, start time: 2023 NFL picks, Week 6 best bets from proven computer simulation model

Both the Los Angeles Rams and Arizona Cardinals look to bounce back after home losses in Week 5 as they face off in an NFC West showdown on Sunday afternoon. Los Angeles (2-3) lost to the Eagles, 23-14, while Arizona fell to Cincinnati, 34-20. The teams split the series last season with both road teams proving victorious. The Rams won the first meeting in Arizona, 20-12, while the Cardinals won in LA, 27-17.

Kickoff at SoFi Stadium in Los Angeles is scheduled for 4:25 p.m. ET. The Rams are a 7-point favorite and the over/under for total points scored is 47.5 in the latest Cardinals vs. Rams odds. Before making any Rams vs. Cardinals picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2023 NFL season on an incredible 171-119 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 25-11 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

Now, the model has set its sights on Cardinals vs. Rams. We can tell you the model is leaning Under on the point total, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Rams vs. Cardinals, and which side of the spread has all the value? Join SportsLine right now to find out which side of the Cardinals vs. Rams spread is a MUST-BACK, all from the model on a 171-119 roll on NFL picks!