The Arizona Cardinals (10-2) command the NFC West and will face their biggest threat to their division title in Week 14. They'll host the Los Angeles Rams (8-4) at State Farm Stadium on Monday Night Football. Arizona is a three-point favorite in Caesars Sportsbook's latest Rams vs. Cardinals odds, while the Over-Under for total points is 51. Kickoff is set for 8:15 p.m. ET. 

Before making any Rams vs. Cardinals picks or any other NFL predictions, you NEED to see what the SportsLine Projection Model has to say.

The model, which simulates every NFL game 10,000 times, is up almost $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 14 of the 2021 season on an incredible 132-94 run on top-rated NFL picks that dates back to the 2017 season. 

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP! 

The model knows the Rams are dangerous through the air. Los Angeles has dealt with significant injuries at wide receiver, but still ranked third overall in passing yards after Week 13. Only the Tampa Bay Buccaneers have more passing touchdowns, so the home team's secondary will have to be on its toes.

The model also knows Arizona's defense has been stellar. The Cardinals have given up the fourth-fewest points in the NFL. Only the Buffalo Bills and Carolina Panthers have given up fewer passing yards this season, and only four teams have tallied more takeaways.

Now, it has simulated Rams vs. Cardinals 10,000 times and the results are in. We can tell you that the model is leaning under, and it also says one side of the spread cashes in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in your own picks. 

Who wins Rams vs. Cardinals on Monday Night Football? And which side of the spread cashes well over 50 percent of the time? ... Join SportsLine right now to see which side of the Rams vs. Cardinals spread to jump on, all from the model that has crushed its NFL picks!