Purdue vs. Iowa odds, line, spread: Proven model reveals college football picks, predictions for Week 10, 2022

A Big Ten battle is on tap between the Purdue Boilermakers and the Iowa Hawkeyes at noon ET on Saturday at Ross-Ade Stadium. Purdue had its four-game winning streak snapped in a 35-24 loss to Wisconsin last week, so it still needs one more win to become bowl eligible. The Boilermakers are favored by 3.5 points in the latest Purdue vs. Iowa odds from Caesars Sportsbook, while the over/under is set at 39.5. 

Before you make any Iowa vs. Purdue picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Purdue vs. Iowa 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Purdue vs. Iowa? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.