The Purdue Boilermakers and Fresno State Bulldogs will both be trying to get off to a hot start when they square off on Saturday afternoon. Purdue reached the Big Ten title game last year, while Fresno State won its final nine games and claimed the Mountain West Conference title. Both teams have a new quarterback under center to open the 2023 season in what is the first-ever meeting between these programs. 

Kickoff at Ross-Ade Stadium in West Lafayette is set for noon ET. The Boilermakers are 3.5-point favorites in the latest Purdue vs. Fresno State odds, per SportsLine consensus, while the over/under for total points scored is 47.5. 

Before making any Fresno State vs. Purdue picks or college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that Purdue is having to replace quarterback Aidan O'Connell, who threw for 3,490 yards and 22 touchdowns last season. The Boilermakers brought in Texas transfer Hudson Card, who played in 20 games and started five in the last two years with the Longhorns. Card has thrown 11 touchdowns and just two interceptions in 194 career attempts.  

The model also knows that Fresno State rattled off nine consecutive wins following its 1-4 start last year, giving the Bulldogs the third-longest active winning streak in the FBS. They claimed the Mountain West Conference title and won the LA Bowl during their 10-win campaign. However, they lost their top passer, top runner and top three receivers from that team. 

Now, the model has set its sights on Purdue vs. Fresno State. We can tell you it is leaning Over on the total, and it also says one side of the spread hits well over 50% of the time! You ABSOLUTELY need to see it before locking in any college football picks!

Who wins Fresno State vs. Purdue, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the Purdue vs. Fresno State spread you should be all over on Saturday, all from the model that's up nearly $2,500 on top-rated CFB spread picks!