The 25th-ranked Florida State Seminoles look to snap a two-game losing streak when they battle the Pittsburgh Panthers in a key Atlantic Coast Conference matchup on Saturday. Pittsburgh is coming off a 48-7 win over Boston College, while Florida State dropped a 28-22 decision to Miami last week. The Panthers (3-2, 1-1 ACC), who are tied for sixth in the conference, are 0-1 on the road this year. The Seminoles (3-2, 0-2 ACC), who are 16th in the league, are 3-1 on their home field in 2025.

Kickoff from Doak Campbell Stadium in Tallahassee, Fla., is at noon ET. Pittsburgh leads the all-time series 6-5. The Seminoles are 10-point favorites in the latest Pittsburgh vs. Florida State odds, while the over/under for total points scored is 57.5 via SportsLine consensus. 

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The model has simulated Pittsburgh vs. Florida State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in over 60% of simulations!

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