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    Pittsburgh vs. Duke odds, line, spread: Proven model reveals college football picks, predictions for Week 12, 2022

    The SportsLine projection model has a pick for the clash between Duke and Pittsburgh. Here are the results:
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    An ACC battle is on tap between the Pittsburgh Panthers and the Duke Blue Devils at noon ET on Saturday at Acrisure Stadium. Duke is riding a three-game winning streak following a blowout win over Virginia Tech last week. The Panthers are favored by 7.5 points in the latest Pittsburgh vs. Duke odds from Caesars Sportsbook, while the over/under is set at 49.5. 

    Before you make any Duke vs. Pittsburgh picks, you'll want to see the college football predictions from the SportsLine Projection Model.

    The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

    Now, it has simulated Pittsburgh vs. Duke 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You absolutely need to see it before locking in your own picks.

    So who wins Pittsburgh vs. Duke? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!

    GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

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    SportsLine Staff

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