Pistons vs. Cavaliers odds, line, spread: Proven model reveals NBA picks, predictions for Nov. 4, 2022

A Central Division battle is on tap between the Detroit Pistons and the Cleveland Cavaliers at 7 p.m. ET Friday at Little Caesars Arena. The Cavaliers extended their winning streak to six games with an overtime victory against Boston on Wednesday. Cleveland is favored by 6.5 points in the latest Pistons vs. Cavaliers odds from Caesars Sportsbook, while the over/under is set at 221. 

Before you make any Cavaliers vs. Pistons picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four seasons. The model enters Week 3 of the 2022-23 NBA season on a stunning 97-65 roll on all top-rated NBA picks that dates back to last season, returning more than $2,400. Anyone following it has seen huge returns.

Now, it has simulated Pistons vs. Cavaliers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

So who wins Pistons vs. Cavaliers? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks... If you're already a member, see the picks below!