Pirates vs. Cardinals odds, picks: Advanced computer MLB model releases selections for Tuesday matchup

The Pittsburgh Pirates and St. Louis Cardinals get together for the first game of a doubleheader at 1:15 p.m. ET on Tuesday. St. Louis is listed as a -160 favorite (risk $160 to win $100) at Caesars Sportsbook, while the Over-Under is set at nine (see up-to-date odds for every game this week on our MLB odds page). 

Before making any Pirates vs. Cardinals picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 55-42 roll on top-rated MLB money-line picks through 10 weeks, returning over $600 for $100 players. Anyone following it has seen HUGE returns!

The model knows the Pirates have some edges on Tuesday afternoon. Pittsburgh has 10 triples this season, ranking third in the National League. The Pirates are also facing a vulnerable starting pitcher in Matthew Liberatore, who has a 5.54 ERA this season. Pittsburgh starter JT Brubaker has a 3.18 ERA in the last four starts, and he has been better on the road than at home in 2022. 

The model also knows the Cardinals have the much better offense. St. Louis leads the NL in stolen bases with 47, and the Cardinals avoid strikeouts at the No. 2 rate in the league. The Cardinals also rank in the top four of the NL in runs, hits, and doubles, with top-five marks in batting average and on-base percentage. St. Louis also has home-field advantage on Tuesday, and the Cardinals have a bullpen that has a 3.84 ERA this season.

Now, it has set its sights on Pirates vs. Cardinals. We can tell you the model is leaning under the total, and it also says one team has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Pirates vs. Cardinals? And which team has ALL the value on the money line? ... Join SportsLine right now to find out which side of the Pirates vs. Cardinals matchup you should be all over Tuesday, all from the model on a roll on MLB picks!