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Phillies vs. Dodgers odds, line, start time, picks, best bets for NLDS Game 4 matchup from proven model

SportsLine's projection model, which is on a 35-29 roll on top-rated MLB money-line picks, has locked in its MLB picks for the Philadelphia Phillies vs. Los Angeles Dodgers matchup on Thursday at Dodger Stadium in Los Angeles

ByPublished: Oct 09, 2025 8:30PM UTC . 2 min read

The Los Angeles Dodgers look to close out their National League Division Series when they take on the Philadelphia Phillies in Game 4 of their best-of-five series on Thursday. Philadelphia staved off elimination with an 8-2 win in Game 3 on Wednesday. The Phillies (96-66), the second seed in the NL, are 42-40 on the road this season, including the playoffs. The Dodgers (93-69), the third seed, are 54-30 on their home field in 2025.

First pitch from Dodger Stadium in Los Angeles is set for 6:08 p.m. ET. The Phillies have won seven of the past 10 meetings with the Dodgers. Los Angeles is a -133 favorite on the money line (risk $133 to win $100) in the latest Phillies vs. Dodgers odds from DraftKings Sportsbook, with Philly the +112 underdog (risk $100 to win $112). The total number of runs Vegas thinks will be scored, or the over-under, is 8. in the latest MLB odds. 

Before you make any Phillies vs. Dodgers picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times.  It enters the 2025 MLB playoffs a profitable 35-29  on top-rated MLB money-line picks this season. It has excelled making home run prop picks this season, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has simulated Phillies vs. Dodgers 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

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Daniel Kohn

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