A Big Ten battle is on tap between the No. 11 Penn State Nittany Lions and the Michigan State Spartans at 4 p.m. ET on Saturday at Beaver Stadium. Michigan State has won six of the last nine matchups between these teams, but it is a heavy underdog this year. The Nittany Lions are favored by 18.5 points in the latest Penn State vs. Michigan State odds from Caesars Sportsbook, while the over/under is set at 52.5. 

Before you make any Michigan State vs. Penn State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

Now, it has simulated Penn State vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Penn State vs. Michigan State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!