The Penn State Nittany Lions (3-3) and the Iowa Hawkeyes (4-2) play in a Big Ten showdown on Saturday. The Nittany Lions have dropped three straight games, which led to James Franklin getting fired. Last weekend, the Hawkeyes completely dominated Wisconsin en route to 37-0 win. 

Kickoff from the Kinnick Stadium in Iowa City, Iowa, is at 7 p.m. ET. The Hawkeyes are 3-point favorites in the latest Penn State vs. Iowa odds, while the over/under for total points scored is 41.5 via SportsLine consensus. 

Before making any Penn State vs. Iowa picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 39-27 combined on money-line and over/under picks since the beginning of 2024. Anyone following could have seen impressive returns.

The model has simulated Penn State vs. Iowa 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in nearly 60% of simulations!

So who wins Penn State vs. Iowa, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!