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Packers vs. Commanders prediction, line, odds: Proven model releases spread pick for 2025 NFL Week 2 Thursday Night Football

The SportsLine projection model, which is 33-17 on top-rated picks since last season, reveals Commanders vs. Packers picks for Thursday Night Football in NFL Week 2

ByPublished: Sep 11, 2025 10:04PM UTC . 2 min read

A pair of NFC contenders will meet on Thursday Night Football in Week 2 as the Green Bay Packers host the Washington Commanders. Both teams are 1-0 after notching divisional wins in Week 1, with Green Bay defeating Detroit, 27-13, while Washington knocked off the Giants, 21-6. Washington went 12-5 last season, while Green Bay was one game behind at 11-6. The Packers lead the all-time series 22-17-1, but the Commanders won the last matchup in 2023. Washington is seeking its first win at Lambeau since 1986.

Kickoff is at 8:15 p.m. ET from Lambeau Stadium in Green Bay, Wis. Green Bay is a 3-point favorite in the latest Commanders vs. Packers odds, after opening as 1.5-point favorites. The over/under for total points scored is 49, making it the second-highest Week 2 NFL total. Green Bay is at -172 on the money line (risk $172 to win $100), while Washington is at +145 (risk $100 to win $145). Before making any Packers vs. Commanders picks or Thursday Night Football predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a 33-17 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Commanders vs. Packers on Thursday Night Football.

We can tell you it's leaning Over the point total, but also says that one side of the spread hits in well over 60% of simulations in an A-rated pick! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

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Ross Kelly

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