Teams trending in opposite directions meet when the Baltimore Orioles battle the Minnesota Twins on Thursday. The Orioles (13-22), who have lost four in a row, are 5-13 on the road this season. The Twins (17-20), who have won four straight, are 11-6 on their home field in 2025.

First pitch from Target Field in Minneapolis is set for 1:10 p.m. ET. Minnesota is a -148 favorite on the money line (risk $148 to win $100) in the latest Orioles vs. Twins odds, while the total number of runs Vegas thinks will be scored, or the over/under, is 8.5. 

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The model has simulated Orioles vs. Twins 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

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