Oregon vs. Indiana odds, line: 2026 College Football Playoff picks for semifinal matchup from proven expert

The top-seeded Indiana Hoosiers take on the fifth-seeded Oregon Ducks in the 2026 Chick-fil-A Peach Bowl, which also serves as the College Football Playoff semifinal matchup, on Friday. Oregon raced past James Madison and Texas Tech to advance to the semis. Indiana had a bye and then smothered Alabama 38-3 in the quarterfinals to make it to this point. The winner advances to face Miami in the national title game on Jan. 19.

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Kickoff is at Mercedes-Benz Stadium at 7:30 p.m. ET. The latest Oregon vs. Indiana odds list the Hoosiers as 3-point favorites. The over/under for total points is 49.5. 

Before making any Indiana vs. Oregon picks, be sure to check out what SportsLine expert Micah Roberts as to say.

Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos' book director. Armed with an elaborate network of sources, Roberts has unmatched info in multiple sports. He's been especially dialed in on Curt Cignetti and Indiana, going 6-1 on his past seven picks involving the Hoosiers. Anyone who has followed him could be WAY UP!

Now Roberts has analyzed Indiana vs. Oregon. He is leaning Under on the total, and he's found a critical x-factor that has him jumping all over one side of the spread. 

Who wins Oregon vs. Indiana, and what critical x-factor makes one side of the spread hit hard? Join SportsLine here to find out which side of the spread to back, all from the expert who has nailed six of his past seven Indiana picks!

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