The No. 1 Auburn Tigers (25-2) have the Ole Miss Rebels (19-8) coming into town for an SEC tilt on Wednesday. The Rebels are on a two-game losing skid. Vanderbilt defeated Ole Miss 77-72 on Feb. 22. It's a different story for the Tigers, who've won four straight matchups. Auburn beat the Georgia Bulldogs 82-70 on Saturday. 

Tipoff is scheduled for 7 p.m. ET at Neville Arena in Auburn, Ala. The Tigers are 13.5-point favorites in the latest Ole Miss vs. Auburn odds from SportsLine consensus, while the over/under for total points scored is 152.5. Auburn is a -1124 money-line favorite (risk $1,124 to win $100).

Before entering any Ole Miss vs. Auburn picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 17 of the 2024-25 season on a 220-160 roll (+2005) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Ole Miss vs. Auburn 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in nearly 60% of simulations!

So who wins Ole Miss vs. Auburn, and which side of the spread hits in nearly 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!