Ole Miss vs. Mississippi State 'Egg Bowl' odds, line: 2025 college football picks for Week 14 predictions from proven model

The sixth-ranked Ole Miss Rebels take on the Mississippi State Bulldogs in the 98th version of the "Egg Bowl" in a key Southeastern Conference matchup on Friday. Ole Miss is coming off a 34-24 win over Florida on Nov. 15, while Mississippi State dropped a 49-27 decision at Missouri that same day. The Rebels (10-1, 6-1 SEC), who are tied for third in the conference, have won four in a row and are 2-1 on the road this season. The Bulldogs (5-6, 1-6 SEC), who are tied for 13th in the league, are 3-3 on their home field in 2025.

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Kickoff from Davis Wade Stadium in Starkville, Miss., is at noon ET. Ole Miss leads the all-time series 66-49-6. The Rebels are 7.5-point favorites in the latest Ole Miss vs. Mississippi State odds, while the over/under for total points scored is 62.5 via SportsLine consensus. 

Before making any Ole Miss vs. Mississippi State picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.

The model has simulated Ole Miss vs. Mississippi State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in well over 60% of simulations!

So who wins Ole Miss vs. Mississippi State, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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